Breast cancer is the most common cancer type in women worldwide. It is estimated that 70% of patients with breast cancer are estrogen receptor (ER)-positive, making hormonal therapies using ER antagonists and degraders, such as tamoxifen and fulvestrant, common treatments for breast cancer. However, therapies with ER-independent mechanisms are needed as approximately 30% of breast…

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Approximately 40% of NSCLC patients are diagnosed with stage IV after the tumor has metastasized. As NSCLC is less sensitive to chemotherapy compared to small cell lung cancer (SCLC), research focus has focused on the development of immunotherapies using monoclonal antibodies (mABs).…

Radiation therapy is one of the most common treatments for cancer. In order to improve the treatment efficacy of radiation therapies, radiobiology is the field of basic research that studies the cellular and molecular biological factors influencing the response of cancerous and normal cell lines to ionizing radiation. In a typical radiobiology experiment, a cell…